Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | TRHR | P34981 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273785 | 0.83 | TRHR (0.56) | ACEOPRM1TRHR | |
| SCHEMBL5710967 | 0.83 | ACE (0.61) | ACEOPRM1TRHRACE2 | |
| SCHEMBL8250626 | 0.81 | OPRM1 (0.60) | ACEOPRM1 | |
| SCHEMBL9746209 | 0.81 | KMT2A (0.48) | TRHR | |
| SCHEMBL7644944 | 0.79 | TRHR (0.71) | TRHR | |
| Morphiceptin SCHEMBL30523887 | 0.79 | OPRM1 (0.81) | OPRM1 | |
| SCHEMBL4955742 | 0.79 | TRHR (0.71) | TRHR | |
| Morphiceptin SCHEMBL30128493 | 0.79 | OPRM1 (0.81) | OPRM1 | |
| SCHEMBL8265844 | 0.79 | ACE (0.65) | ACEOPRM1ACE2 | |
| SCHEMBL13533686 | 0.79 | ACE (0.65) | ACEOPRM1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | claimed |