Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | TERT | O14746 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448232 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL28772907 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL10344107 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL27436356 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL28945766 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL10344108 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL11511124 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL182419 | 0.98 | PPARG (0.58) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL2754267 | 0.95 | PPARG (0.55) | PPARGPPARATERTGMNNUSP2 | |
| SCHEMBL3264128 | 0.95 | PPARG (0.55) | PPARGPPARATERTGMNNUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303109-A1 | Novel Analogs of Curcumin and Methods of Use | SARKAR FAZLUL H (US) | 2014-10-09 | — | — | US | disclosed |
| WO-2011142795-A9 | NOVEL ANALOGS OF CURCUMIN AND METHODS OF USE | WAYNE STATE UNIVERSITY (US) | 2011-12-22 | — | — | WO | disclosed |
| WO-2011142795-A1 | NOVEL ANALOGS OF CURCUMIN AND METHODS OF USE | WAYNE STATE UNIVERSITY (US) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303109-A1 | Novel Analogs of Curcumin and Methods of Use | KLHL6, KEAP1, SOD1 | PPARG 1298/4885PPARA 688/4885TERT 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.