Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754267 | 1.00 | PPARG (0.55) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL2754266 | 1.00 | PPARG (0.55) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL10344107 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL182419 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL27436356 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL28772907 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL10344108 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL29448232 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL11511124 | 0.98 | PPARG (0.58) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL9501897 | 0.98 | PPARG (0.53) | PPARGPPARATERTMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029763-A1 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | UNIVERSIDADE BANDEIRANTE DE SAO PAULO-ACADEMIA, PAULISTA ANCHIETA S/C LTDA (BR) | 2010-02-04 | — | — | US | claimed |
| EP-2054365-A2 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | Uniban - Universidade Bandeirante De São Paulo (BR) | 2009-05-06 | — | — | EP | claimed |
| WO-2008003155-A2 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | UNIBAN - UNIVERSIDADE BANDEIRANTE DE SÃO PAULO - ACADEMIA PAULISTA ANCHIETA S/C LTDA (BR) | 2008-01-10 | — | — | WO | claimed |
| US-5489623-A | APPLYING POLYMER TO SURFACE, EXPOSING TO INCIDENT PHOTONICRADIATION TO RENDER PORTIONS LESS SOLUBLE OR DISPERSIBLE | THE DOW CHEMICAL COMPANY (US) | 1996-02-06 | — | — | US | claimed |
| EP-0676062-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1995-10-11 | — | — | EP | claimed |
| US-5426164-A | Solvent and chemical resistant coatings and photoresists; photocuring of perfluorovinyl polymers containing photo active sites; cyclization | THE DOW CHEMICAL COMPANY (US) | 1995-06-20 | — | — | US | claimed |
| WO-1994015258-A1 | PHOTODEFINABLE POLYMERS CONTAINING PERFLUOROCYCLOBUTANE GROUPS | THE DOW CHEMICAL COMPANY (US) | 1994-07-07 | — | — | WO | claimed |
| EP-0374099-B1 | VERY THIN PALLADIUM ZERO COMPLEX LAYERS | CIBA-GEIGY AG (CH) | 1993-05-05 | — | — | EP | claimed |
| CN-110128408-B | Quinoxaline-containing pentadiene ketoxime ether compounds and preparation method and application thereof | 贵州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109942540-B | 1, 4-pentadiene-3-ketone derivative containing thiophene sulfonate, preparation method and application thereof | 贵州大学 | 2021-06-18 | — | — | CN | disclosed |
| US-10363230-B2 | 6-shogaol derivatives and activities thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2019-07-30 | — | — | US | disclosed |
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180280320-A1 | 6-SHOGAOL DERIVATIVES AND ACTIVITIES THEREOF | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2018-10-04 | — | — | US | disclosed |
| US-20180271804-A1 | 6-SHOGAOL DERIVATIVES AND ACTIVITIES THEREOF | NORTH CAROLINA AGRICULTURAL AND TECHNICAL STATE UNIVERSITY (US) | 2018-09-27 | — | — | US | disclosed |
| WO-2004047716-A2 | NEW METHOD FOR THE PREPARATION OF 1,5-BIS(4-HYDROXY-3-METOXY-PHENYL)-PENTA-1,4-DIEN-3-ONE AND DERIVATIVES WITH ANTITUMORAL PROPERTIES | Fundação De Amparo À Pesquisa Do Estado de São Paulo (BR) | 2004-06-10 | — | — | WO | disclosed |
| US-5236797-A | Good solubility, dispersibility, dark decay | EASTMAN KODAK COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-5187304-A | 1,5-Bis/4-carboxycyclohexyl/-3-pentanol and derivatives as monomers for polyester coatings or molding materials | EASTMAN KODAK COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| US-5144003-A | Curable copolymers containing 1,5-bis(4-carboxycyclohexyl)-3-pentanol monomer; castings and moldings | EASTMAN KODAK COMPANY (US) | 1992-09-01 | — | — | US | disclosed |
| US-5025086-A | Hardness, flexibility | EASTMAN KODAK COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| US-4521629-A | REACTINGH AN AROMATIC ALDEHYDE WITH ACETONE | AMERICAN CYANAMID COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180280320-A1 | 6-SHOGAOL DERIVATIVES AND ACTIVITIES THEREOF | NFE2L2, HMOX1, KEAP1 | PPARG 30/4885PPARA 109/4885TERT 2608/4885 |
| US-20180271804-A1 | 6-SHOGAOL DERIVATIVES AND ACTIVITIES THEREOF | NFE2L2, HMOX1, KEAP1 | PPARG 30/4885PPARA 109/4885TERT 2608/4885 |
| US-20100029763-A1 | METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES | CASP3, CYP8B1, DERA | PPARG 3389/4885PPARA 1428/4885TERT 1780/4885 |
| US-10363230-B2 | 6-shogaol derivatives and activities thereof | NFE2L2, HMOX1, KEAP1 | PPARG 30/4885PPARA 109/4885TERT 2608/4885 |
| US-10342766-B2 | 6-shogaol derivatives and activities thereof | NFE2L2, HMOX1, KEAP1 | PPARG 30/4885PPARA 109/4885TERT 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.