Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9013331 | 0.78 | HTR6 (0.60) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL9013611 | 0.77 | MAPT (0.54) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL27995023 | 0.76 | — | — | |
| SCHEMBL27994773 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9013362 | 0.76 | MAPT (0.52) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| SCHEMBL27994806 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9013554 | 0.76 | — | — | |
| SCHEMBL13603916 | 0.74 | MEN1 (0.54) | MEN1CYP1A2MAPTCYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL9013623 | 0.74 | — | — | |
| SCHEMBL8134255 | 0.74 | MEN1 (0.70) | MEN1CYP1A2MAPTCYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | claimed |
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |