Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 7/20 | 0.60 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272135 | 0.93 | YAP1 (0.58) | YAP1GPR119ITGB3ITGA2BKDM4E | |
| SCHEMBL9312168 | 0.88 | YAP1 (0.55) | YAP1GPR119ITGB3ITGA2BKDM4E | |
| SCHEMBL7313782 | 0.81 | YAP1 (0.63) | YAP1GPR119ITGB3ITGA2BKDM4E | |
| SCHEMBL7309801 | 0.81 | YAP1 (0.63) | YAP1GPR119ITGB3ITGA2B | |
| SCHEMBL7358570 | 0.80 | CA12 (0.46) | ITGB3ITGA2BKDM4E | |
| SCHEMBL7282664 | 0.79 | YAP1 (0.72) | YAP1GPR119ITGB3ITGA2B | |
| SCHEMBL7272131 | 0.79 | YAP1 (0.71) | YAP1ITGB3ITGA2B | |
| SCHEMBL7315176 | 0.78 | YAP1 (0.59) | YAP1GPR119ITGB3ITGA2B | |
| SCHEMBL7312363 | 0.78 | GPR119 (0.62) | YAP1GPR119ITGB3ITGA2B | |
| SCHEMBL7315022 | 0.78 | GPR119 (0.64) | YAP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478363-B1 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO INC (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |
| WO-1993019046-A1 | NOVEL SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1993-09-30 | — | — | WO | disclosed |
| EP-0478363-A2 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |