Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGH | Q92820 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274405 | 1.00 | GGH (0.52) | GGHCYP1A2GAANAALAD2EPHX1 | |
| SCHEMBL20189708 | 0.84 | KMT2A (0.51) | GGHCYP1A2GAAEPHX1MMP9 | |
| SCHEMBL20189709 | 0.84 | KMT2A (0.51) | GGHCYP1A2GAAEPHX1MMP9 | |
| SCHEMBL27657427 | 0.82 | RAB9A (0.47) | CYP1A2GAAEPHX1MAPTNPC1 | |
| SCHEMBL60370 | 0.81 | GAA (0.62) | GGHGAANAALAD2MMP9MMP8 | |
| SCHEMBL60371 | 0.81 | GAA (0.62) | GGHGAANAALAD2MMP9MMP8 | |
| SCHEMBL2820711 | 0.81 | PPARG (0.54) | CYP1A2GAAEPHX1MAPTNPC1 | |
| SCHEMBL27469903 | 0.81 | PPARG (0.54) | CYP1A2GAAEPHX1MAPTNPC1 | |
| SCHEMBL5342232 | 0.78 | RAB9A (0.50) | CYP1A2GAAEPHX1MAPTNPC1 | |
| SCHEMBL5342235 | 0.78 | RAB9A (0.50) | CYP1A2GAAEPHX1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |