Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271564 | 0.95 | TRHR (0.47) | TRHRKMT2ACAPN1CTSB | |
| SCHEMBL7273117 | 0.83 | TRHR (0.47) | TRHRCAPN1 | |
| SCHEMBL7273766 | 0.82 | TRHR (0.47) | TRHR | |
| SCHEMBL7282889 | 0.82 | TRHR (0.46) | TRHR | |
| SCHEMBL7273522 | 0.82 | CAPN1 (0.44) | TRHRKMT2ACAPN1CTSB | |
| Posatirelin SCHEMBL3083636 | 0.81 | TRHR (0.68) | TRHR | |
| Posatirelin SCHEMBL195247 | 0.81 | TRHR (0.68) | TRHR | |
| SCHEMBL7272408 | 0.81 | TRHR (0.46) | TRHR | |
| SCHEMBL7429679 | 0.80 | TRHR (0.45) | TRHR | |
| SCHEMBL9746209 | 0.80 | KMT2A (0.48) | TRHRKMT2ACAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |