Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274499 | 1.00 | ALDH1A1 (0.41) | ALDH1A1PSMD10STAT3FKBP1ACYP24A1 | |
| SCHEMBL29316353 | 0.83 | TSHR (0.51) | ALDH1A1PSMD10STAT3FKBP1ACYP24A1 | |
| SCHEMBL1933322 | 0.82 | TSHR (0.49) | ALDH1A1PSMD10STAT3FKBP1ACYP24A1 | |
| SCHEMBL13740848 | 0.81 | PSMD10 (0.44) | ALDH1A1PSMD10STAT3FKBP1ACYP24A1 | |
| SCHEMBL9709447 | 0.80 | ALDH1A1 (0.51) | ALDH1A1PSMD10STAT3KMT2APOLB | |
| SCHEMBL4812770 | 0.79 | ALDH1A1 (0.48) | ALDH1A1PSMD10STAT3CYP24A1CA12 | |
| SCHEMBL4951882 | 0.79 | ALDH1A1 (0.48) | ALDH1A1PSMD10STAT3CYP24A1CA12 | |
| SCHEMBL11050599 | 0.79 | ALDH1A1 (0.48) | ALDH1A1PSMD10STAT3CYP24A1CA12 | |
| SCHEMBL4815560 | 0.79 | ALDH1A1 (0.48) | ALDH1A1PSMD10STAT3CYP24A1CA12 | |
| SCHEMBL8484861 | 0.79 | ALDH1A1 (0.48) | ALDH1A1PSMD10STAT3CYP24A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174131-A2 | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them | FISONS plc (GB) | 1986-03-12 | — | — | EP | disclosed |