Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 8/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274036 | 0.93 | ACHE (0.39) | CHRM4ACHECHRM2CHRM1L3MBTL1 | |
| SCHEMBL7284054 | 0.90 | ACHE (0.40) | ACHE | |
| SCHEMBL7280009 | 0.84 | ACHE (0.41) | CHRM4ACHE | |
| SCHEMBL7272609 | 0.84 | ACHE (0.40) | ACHE | |
| SCHEMBL7281844 | 0.83 | ACHE (0.40) | ACHE | |
| SCHEMBL7274844 | 0.83 | CHRM4 (0.41) | CHRM4ACHECHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7274799 | 0.82 | DCPS (0.41) | ACHEL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7274804 | 0.82 | DCPS (0.41) | ACHEL3MBTL1 | |
| SCHEMBL7280792 | 0.82 | ACHE (0.40) | ACHE | |
| SCHEMBL7274685 | 0.80 | ACHE (0.45) | ACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481429-B1 | Quinoline derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| EP-0987262-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5300517-A | Treating Alzheimer's | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5240934-A | Cognition activators | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| US-5190951-A | Inhibitors of acetylcholinesterase, treatment of senile dementia | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |
| EP-0481429-A2 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |