Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 5/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | F12 | P00748 | 1/20 | 0.56 |
| ▸ | F7 | P08709 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.54 |
| ▸ | C1S | P09871 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876947 | 0.97 | TP53 (0.63) | TP53TSHRF2F10F12 | |
| Hydrochloric Acid SCHEMBL394084 | 0.95 | BLM (0.61) | TP53TSHRF2F10F12 | |
| SCHEMBL3442777 | 0.91 | WDR5 (0.68) | TP53TSHRF2F10F12 | |
| Hydrochloric Acid SCHEMBL8994023 | 0.89 | PARP15 (0.59) | TP53TSHRF2F10F12 | |
| Benzamidine SCHEMBL10816513 | 0.88 | F2 (0.76) | TP53TSHRF2F10F12 | |
| Terephthalic Acid SCHEMBL7555569 | 0.87 | TSHR (0.71) | TP53TSHRF2PRSS1PRSS3 | |
| Terephthalic Acid SCHEMBL27473772 | 0.81 | TSHR (0.80) | TP53TSHRSRD5A2CA12CA1 | |
| Terephthalic Acid SCHEMBL17667155 | 0.81 | TSHR (0.92) | TP53TSHRSRD5A2CA12CA1 | |
| Terephthalic Acid SCHEMBL27626586 | 0.81 | TSHR (0.92) | TP53TSHRSRD5A2CA12CA1 | |
| SCHEMBL537030 | 0.81 | LMNA (0.77) | F2F10F12F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317959-A2 | Anti-ulcer composition | Okamoto, Shosuke (JP) | 1989-05-31 | — | — | EP | disclosed |