Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
| ▸ | IL6ST | P40189 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359905 | 0.91 | HTT (0.51) | POLBOXER1HTTCREBBPIL6ST | |
| SCHEMBL27385284 | 0.87 | POLB (0.43) | POLBOXER1HTTCREBBPIL6ST | |
| SCHEMBL7276946 | 0.87 | POLB (0.43) | POLBOXER1HTTCREBBPIL6ST | |
| SCHEMBL29424269 | 0.83 | HTR2A (0.59) | POLBOXER1HTTCREBBPKDM4E | |
| SCHEMBL7528710 | 0.83 | HTR2A (0.59) | POLBOXER1HTTCREBBPKDM4E | |
| SCHEMBL12301581 | 0.82 | CREBBP (0.52) | POLBOXER1HTTCREBBPKDM4E | |
| SCHEMBL30569636 | 0.81 | L3MBTL1 (0.63) | POLBOXER1CREBBPIL6STMEN1 | |
| SCHEMBL3165284 | 0.81 | L3MBTL1 (0.63) | POLBOXER1CREBBPIL6STMEN1 | |
| SCHEMBL24878392 | 0.81 | HTR6 (0.54) | POLBOXER1HTTCREBBPKDM4E | |
| SCHEMBL24877781 | 0.81 | HTR6 (0.58) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512831-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0478362-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0512829-B1 | Fibrinogen receptor antagonists | MERCK & CO INC (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5455243-A | Anticoagulants | MERCK & CO., INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5321034-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5281585-A | Secondary amide containing antagonist | MERCK & CO., INC. (US) | 1994-01-25 | — | — | US | disclosed |
| US-5264420-A | Anticoagulants | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |
| CN-1067883-A | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1993-01-13 | — | — | CN | disclosed |
| WO-1992019595-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1992-11-12 | — | — | WO | disclosed |
| EP-0512829-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0512831-A1 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| EP-0478362-A2 | Fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |