Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 10/20 | 0.41 |
| ▸ | HRH1 | P35367 | 10/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272380 | 0.87 | MMP2 (0.41) | CHRNA7HRH2HRH1HRH3MMP2 | |
| SCHEMBL7276904 | 0.86 | MMP2 (0.39) | CHRNA7HRH2HRH1HRH3MMP2 | |
| SCHEMBL7272704 | 0.85 | POLB (0.39) | CHRNA7HRH2HRH1HRH3MMP2 | |
| SCHEMBL7275606 | 0.85 | MMP2 (0.42) | CHRNA7HRH2HRH1HRH3MMP2 | |
| SCHEMBL7283917 | 0.84 | SLC6A7 (0.40) | CHRNA7MMP2MMP3EGLN1MMP1 | |
| SCHEMBL7275597 | 0.84 | KDM4E (0.40) | CHRNA7HRH2HRH1HRH3MMP2 | |
| SCHEMBL7272754 | 0.84 | MMP2 (0.41) | CHRNA7HRH2HRH1HRH3MMP2 | |
| Hydrochloric Acid SCHEMBL7283737 | 0.83 | ITGB3 (0.46) | — | |
| SCHEMBL7283484 | 0.83 | KCNA5 (0.42) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL7282456 | 0.82 | KCNQ1 (0.46) | MMP2MMP3MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |