Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 13/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884482 | 0.86 | MEN1 (0.45) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL7393270 | 0.86 | MEN1 (0.45) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL31419788 | 0.86 | CASP3 (0.46) | CASP3CASP7CASP9CASP6CASP8 | |
| SCHEMBL9800645 | 0.85 | MEN1 (0.41) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL7799440 | 0.76 | SYK (0.44) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL24130649 | 0.76 | MEN1 (0.46) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL16765446 | 0.76 | MEN1 (0.46) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL16790408 | 0.76 | MEN1 (0.46) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL23445969 | 0.75 | FOLH1 (0.47) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL9695489 | 0.75 | FOLH1 (0.47) | MEN1GAAKMT2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518528-A | α Amino fluoro ketones | MP BIOMEDICALS, LLC | 1985-05-21 | — | — | US | disclosed |
| EP-0130679-A2 | Alpha amino fluoro ketones | ENZYME SYSTEMS PRODUCTS INC. (US) | 1985-01-09 | — | — | EP | disclosed |