Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 7/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884482 | 0.90 | MEN1 (0.45) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL7393270 | 0.90 | MEN1 (0.45) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL23332644 | 0.88 | CYP2D6 (0.44) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL23332643 | 0.87 | MAOA (0.43) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL9800543 | 0.86 | MEN1 (0.39) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL7274680 | 0.85 | CASP3 (0.42) | MEN1KMT2AGAACTSSCTSK | |
| SCHEMBL1235160 | 0.84 | CTSK (0.49) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL1235161 | 0.84 | CTSK (0.49) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL4279525 | 0.84 | CTSK (0.49) | CTSSCTSKCTSLCTSBCA1 | |
| SCHEMBL23332621 | 0.82 | SERPINE1 (0.39) | MEN1KMT2AGAACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416373-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-03-13 | — | — | EP | disclosed |