Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7275243 | 0.93 | KMT2A (0.40) | KMT2AL3MBTL1SIGMAR1LMNAHPGD | |
| SCHEMBL7281991 | 0.86 | KMT2A (0.36) | KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL7283087 | 0.84 | KDM1A (0.39) | LMNAHPGDOPRM1OPRD1CHRM4 | |
| SCHEMBL7284971 | 0.84 | KDM1A (0.39) | LMNAHPGDOPRM1OPRD1CHRM4 | |
| SCHEMBL7283082 | 0.84 | KDM1A (0.39) | LMNAHPGDOPRM1OPRD1CHRM4 | |
| SCHEMBL7284740 | 0.83 | CHRM4 (0.37) | LMNAHPGDOPRM1OPRD1CHRM4 | |
| SCHEMBL7281644 | 0.83 | CHRM4 (0.37) | LMNAHPGDOPRM1OPRD1CHRM4 | |
| SCHEMBL7281650 | 0.83 | CHRM4 (0.37) | LMNAHPGDOPRM1OPRD1CHRM4 | |
| SCHEMBL7271758 | 0.82 | SIGMAR1 (0.38) | KMT2AL3MBTL1SIGMAR1OPRM1OPRD1 | |
| SCHEMBL7274528 | 0.82 | SIGMAR1 (0.45) | KMT2ASIGMAR1LMNAHPGDOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |