Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275657 | 0.93 | SIGMAR1 (0.46) | SIGMAR1NAMPTALDH1A1LMNAMAPT | |
| SCHEMBL7283236 | 0.92 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1LMNAMAPTCACNA1G | |
| SCHEMBL7275556 | 0.92 | SIGMAR1 (0.42) | SIGMAR1NAMPTITGB1ITGA5CACNA1G | |
| SCHEMBL7282068 | 0.91 | SIGMAR1 (0.45) | SIGMAR1CACNA1GMEN1KMT2A | |
| SCHEMBL7274234 | 0.90 | SIGMAR1 (0.44) | SIGMAR1HDAC1ALDH1A1LMNAMAPT | |
| SCHEMBL7276087 | 0.89 | SIGMAR1 (0.45) | SIGMAR1NAMPTCACNA1GMEN1KMT2A | |
| SCHEMBL7284966 | 0.87 | SUCNR1 (0.42) | SIGMAR1CACNA1G | |
| SCHEMBL7283872 | 0.86 | SIGMAR1 (0.44) | SIGMAR1NAMPTALDH1A1CACNA1G | |
| SCHEMBL7276578 | 0.86 | SIGMAR1 (0.43) | SIGMAR1NAMPTKMT2A | |
| SCHEMBL7282506 | 0.86 | SIGMAR1 (0.45) | SIGMAR1CACNA1GMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |