Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283872 | 0.93 | SIGMAR1 (0.44) | SIGMAR1CACNA1GNAMPT | |
| SCHEMBL7282506 | 0.92 | SIGMAR1 (0.45) | SIGMAR1CACNA1G | |
| SCHEMBL7274737 | 0.92 | SIGMAR1 (0.43) | SIGMAR1CACNA1GITGB1ITGA5NAMPT | |
| SCHEMBL7284474 | 0.90 | SIGMAR1 (0.41) | SIGMAR1CCKBRGLSBRD4CREBBP | |
| SCHEMBL7275657 | 0.87 | SIGMAR1 (0.46) | SIGMAR1CACNA1GNAMPT | |
| SCHEMBL7283862 | 0.86 | OPRM1 (0.37) | L3MBTL1ADRB2ADRB1ADRB3ITGB1 | |
| SCHEMBL7283236 | 0.86 | SIGMAR1 (0.46) | SIGMAR1CACNA1G | |
| SCHEMBL7282068 | 0.85 | SIGMAR1 (0.45) | SIGMAR1CACNA1G | |
| SCHEMBL7274557 | 0.84 | SIGMAR1 (0.44) | SIGMAR1CACNA1G | |
| SCHEMBL7274234 | 0.84 | SIGMAR1 (0.44) | SIGMAR1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |