Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281854 | 0.98 | DRD4 (0.43) | DRD4F10CHRM4ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7283406 | 0.91 | ACHE (0.41) | DRD4F10CHRM4ITGB3ITGA2B | |
| Water SCHEMBL7275070 | 0.91 | DRD4 (0.42) | DRD4F10ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7281722 | 0.89 | DRD4 (0.40) | DRD4F10CHRM4ITGB3ITGA2B | |
| Water SCHEMBL7271805 | 0.89 | DRD4 (0.41) | DRD4F10ITGB3ITGA2BITGAV | |
| SCHEMBL7277096 | 0.86 | ITGB3 (0.43) | CHRM4ITGB3ITGA2BITGAV | |
| SCHEMBL7274776 | 0.85 | ITGB3 (0.45) | F10ITGB3ITGA2BITGAVPRSS1 | |
| SCHEMBL7275068 | 0.84 | ITGB3 (0.40) | CHRM4ITGB3ITGA2BITGAV | |
| SCHEMBL7275634 | 0.84 | ITGB3 (0.42) | CHRM4ITGB3ITGA2BITGAV | |
| SCHEMBL7272558 | 0.83 | ITGB3 (0.42) | DRD4F10ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |