Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7274984 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7281172 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL7284365 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7274465 | 0.77 | HDAC1 (0.60) | ITGB3ITGA2B | |
| SCHEMBL7283333 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2B | |
| SCHEMBL7283544 | 0.76 | F10 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7401407 | 0.76 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7284267 | 0.75 | APEX1 (0.55) | ITGB3ITGA2BPOLBNQO2 | |
| Hydrochloric Acid SCHEMBL7284383 | 0.74 | ITGB3 (0.43) | ITGB3ITGA2BLMNA | |
| Hydrochloric Acid SCHEMBL7404001 | 0.74 | F10 (0.51) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |