Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7274247 | 0.86 | ITGB3 (0.42) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7275015 | 0.82 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL8407585 | 0.77 | CHRNB2 (0.49) | ITGB3ITGA2BHRH3 | |
| SCHEMBL7274780 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2B | |
| SCHEMBL8410297 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2BHRH3 | |
| SCHEMBL8557864 | 0.75 | ITGB3 (0.49) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7276212 | 0.74 | ITGB3 (0.41) | ITGB3ITGA2BHRH3 | |
| SCHEMBL2565333 | 0.73 | ACE (0.49) | ITGB3ITGA2B | |
| SCHEMBL8410474 | 0.73 | HTR2A (0.53) | ITGB3ITGA2BHRH3 | |
| SCHEMBL8410661 | 0.72 | SLC6A1 (0.48) | ITGB3ITGA2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |