Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274977 | 0.94 | KMT2A (0.38) | LMNAL3MBTL1ALDH1A1TDP1ADRB2 | |
| SCHEMBL7281961 | 0.88 | ITGB3 (0.44) | LMNAL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL7281573 | 0.87 | ITGB3 (0.43) | — | |
| Hydrochloric Acid SCHEMBL7286391 | 0.86 | ITGB3 (0.42) | — | |
| SCHEMBL7282163 | 0.85 | PTPN1 (0.37) | LMNAL3MBTL1ALDH1A1TDP1ADRB2 | |
| SCHEMBL7271729 | 0.83 | RXRA (0.38) | ADRB2ADRB1MAPTMEN1GAA | |
| SCHEMBL7281878 | 0.80 | CYP11B1 (0.46) | LMNAALDH1A1TDP1ADRB2ADRB1 | |
| SCHEMBL7275527 | 0.80 | CYP11B1 (0.46) | LMNAALDH1A1TDP1ADRB2ADRB1 | |
| SCHEMBL7280890 | 0.80 | RPS6KA3 (0.36) | ADRB2ADRB1RPS6KA3HRH3PTPN1 | |
| SCHEMBL7273615 | 0.79 | F2 (0.43) | LMNAL3MBTL1ALDH1A1TDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |