Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084132 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL7284187 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7284176 | 0.80 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL11084218 | 0.78 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL7276081 | 0.77 | ACE (0.35) | ACE | |
| SCHEMBL2308708 | 0.76 | NR1H2 (0.44) | — | |
| SCHEMBL11082017 | 0.74 | YAP1 (0.47) | ITGB3ITGA2B | |
| SCHEMBL20481180 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL20481179 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL22534100 | 0.73 | ATM (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529858-B1 | 2-Piperazinone compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5294713-A | Inhibiting cell adhesion | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0529858-A1 | 2-Piperazinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |