Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276520 | 0.89 | SMN1; SMN2 (0.35) | HTR6SMN1; SMN2PPARDFFAR1PPARA | |
| Water SCHEMBL7275459 | 0.81 | PNMT (0.41) | SMN1; SMN2PKM | |
| Water SCHEMBL7283376 | 0.80 | TBXA2R (0.41) | SMN1; SMN2PKM | |
| SCHEMBL7276108 | 0.79 | TBXA2R (0.40) | SMN1; SMN2ITGB3ITGA2BPKM | |
| SCHEMBL7276521 | 0.79 | PNMT (0.38) | SMN1; SMN2ITGB3ITGA2BPKM | |
| SCHEMBL7273720 | 0.77 | PNMT (0.39) | SMN1; SMN2PKM | |
| SCHEMBL7273778 | 0.76 | TBXA2R (0.39) | SMN1; SMN2PKM | |
| SCHEMBL7273681 | 0.71 | ALDH1A1 (0.44) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7283092 | 0.70 | F10 (0.38) | — | |
| SCHEMBL7282531 | 0.70 | ALDH1A1 (0.45) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |