Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 3/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273778 | 0.90 | TBXA2R (0.39) | PNMTTBXA2RKDM4EALDH1A1LMNA | |
| Water SCHEMBL7275459 | 0.88 | PNMT (0.41) | PNMTTBXA2RALDH1A1SMN1; SMN2PKM | |
| Water SCHEMBL7283376 | 0.86 | TBXA2R (0.41) | PNMTTBXA2RSMN1; SMN2PKM | |
| SCHEMBL7276108 | 0.84 | TBXA2R (0.40) | PNMTTBXA2RSMN1; SMN2PKM | |
| SCHEMBL7276521 | 0.84 | PNMT (0.38) | PNMTTBXA2RSMN1; SMN2PKM | |
| SCHEMBL7283081 | 0.79 | PNMT (0.37) | PNMTTBXA2RKDM4ESMN1; SMN2PKM | |
| SCHEMBL7276520 | 0.78 | SMN1; SMN2 (0.35) | PNMTSMN1; SMN2PKMTP53 | |
| SCHEMBL7276101 | 0.77 | HTR6 (0.45) | SMN1; SMN2PKM | |
| SCHEMBL7285181 | 0.73 | TDP1 (0.45) | ALDH1A1SMN1; SMN2PKMTSHR | |
| SCHEMBL7274663 | 0.72 | ITGB3 (0.40) | ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |