Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270890 | 0.96 | HTR3A (0.48) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL29881195 | 0.82 | HTR3A (0.49) | HTR3AMEN1KMT2AHTR4HTR3E | |
| SCHEMBL7280903 | 0.82 | HTR3A (0.49) | HTR3AMEN1KMT2AHTR4HTR3E | |
| Hydrochloric Acid SCHEMBL7281701 | 0.82 | HTR3A (0.49) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL8940024 | 0.79 | HTR3A (0.52) | HTR3AMEN1KMT2AHTR4HTR3E | |
| SCHEMBL9485758 | 0.78 | HTR3A (0.52) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7270659 | 0.78 | DRD2 (0.52) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7271162 | 0.78 | SLC6A12 (0.56) | HTR3A | |
| Hydrochloric Acid SCHEMBL9484526 | 0.78 | HTR3A (0.51) | HTR3AMEN1KMT2AHTR4 | |
| SCHEMBL7270543 | 0.78 | HTR3A (0.64) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407137-B1 | Benzazine compounds and pharmaceutical uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-05-01 | — | — | EP | disclosed |