Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | FGB | P02675 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816756 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL3789398 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL3786465 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL3785707 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL397261 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL28245636 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL31607650 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL27185986 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL28148154 | 0.81 | CA1 (0.65) | ALDH1A1TDP1ADRA2BPTGS1MAPT | |
| SCHEMBL10813504 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TDP1ADRA2BPTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015454-A1 | HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS | INGEVITY UK LTD (GB) | 2026-01-15 | — | — | US | claimed |
| EP-4594381-A1 | NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE | Ingevity UK Ltd (GB) | 2025-08-06 | — | — | EP | claimed |
| US-20250243313-A1 | POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME | INGEVITY UK LTD (GB) | 2025-07-31 | — | — | US | claimed |
| US-20250230274-A1 | POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME | INGEVITY UK LTD (GB) | 2025-07-17 | — | — | US | claimed |
| WO-2025149744-A1 | POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME | INGEVITY UK LTD (GB) | 2025-07-17 | — | — | WO | claimed |
| US-20240110002-A1 | NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE | INGEVITY UK LTD (GB) | 2024-04-04 | — | — | US | claimed |
| WO-2024068129-A1 | NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE | INGEVITY UK LTD. (GB) | 2024-04-04 | — | — | WO | claimed |
| CN-112812064-A | Organic compound and method for producing the same | 中国科学院广州生物医药与健康研究院 | 2021-05-18 | — | — | CN | claimed |
| US-20260015454-A1 | HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS | INGEVITY UK LTD (GB) | 2026-01-15 | — | — | US | disclosed |
| EP-4594381-A1 | NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE | Ingevity UK Ltd (GB) | 2025-08-06 | — | — | EP | disclosed |
| US-20250243313-A1 | POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME | INGEVITY UK LTD (GB) | 2025-07-31 | — | — | US | disclosed |
| WO-2025149744-A1 | POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME | INGEVITY UK LTD (GB) | 2025-07-17 | — | — | WO | disclosed |
| US-20250230274-A1 | POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME | INGEVITY UK LTD (GB) | 2025-07-17 | — | — | US | disclosed |
| WO-2024068129-A1 | NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE | INGEVITY UK LTD. (GB) | 2024-04-04 | — | — | WO | disclosed |
| EP-0582692-B1 | DIPHOSPHINE LIGANDS | HOFFMANN LA ROCHE (CH) | 1998-04-22 | — | — | EP | disclosed |
| US-5514805-A | ASSYMETRIC HYDROGENATION OF A PYRIDINECARBONYL COMPOUND, RHODIUM PHOSPHINE CATALYST | HOFFMANN-LA ROCHE INC. (US) | 1996-05-07 | — | — | US | disclosed |
| US-5508438-A | Phosphorus compounds | HOFFMANN-LA ROCHE INC. (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0582692-A1 | DIPHOSPHINE LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 1994-02-16 | — | — | EP | disclosed |
| WO-1993015089-A1 | DIPHOSPHINE LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-08-05 | — | — | WO | disclosed |
| EP-0553778-A1 | Asymmetric hydrogenation | F. HOFFMANN-LA ROCHE AG (CH) | 1993-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015454-A1 | HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS | PUF60, MORF4L1, C9 | ALDH1A1 538/4885TDP1 549/4885ADRA2B 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.