Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FGB | P02675 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245636 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 | |
| SCHEMBL3789398 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 | |
| SCHEMBL7276398 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 | |
| SCHEMBL30816756 | 0.83 | ALDH1A1 (0.65) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 | |
| SCHEMBL3785992 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 | |
| SCHEMBL28278715 | 0.81 | TP53 (0.53) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 | |
| SCHEMBL3786475 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL28877117 | 0.79 | CYP3A4 (0.53) | ALDH1A1TDP1CYP3A4TSHRHSD17B10 | |
| SCHEMBL3787196 | 0.78 | MAPK1 (0.41) | ALDH1A1TDP1PTGS1TSHRHSD17B10 | |
| SCHEMBL14656326 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TDP1ADRA2BPTGS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885TDP1 4196/4885ADRA2B 2587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.