Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 5/20 | 0.48 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | CTSE | P14091 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462716 | 0.95 | ADORA3 (0.61) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL7267896 | 0.92 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL7276997 | 0.89 | ADORA3 (0.57) | ADORA3ADORA2AADORA2BADORA1KLK5 | |
| SCHEMBL11760193 | 0.89 | PREP (0.57) | KLK5CMA1PREPCTSLFKBP1A | |
| SCHEMBL8056455 | 0.89 | PREP (0.57) | KLK5CMA1PREPCTSLFKBP1A | |
| SCHEMBL7265704 | 0.87 | PREP (0.61) | KLK5CMA1PREPCTSLFKBP1A | |
| SCHEMBL28545846 | 0.87 | PREP (0.61) | KLK5CMA1PREPCTSLFKBP1A | |
| SCHEMBL10882017 | 0.87 | PREP (0.61) | KLK5CMA1PREPCTSLFKBP1A | |
| SCHEMBL9699149 | 0.87 | PREP (0.61) | KLK5CMA1PREPCTSLFKBP1A | |
| SCHEMBL25133623 | 0.84 | KLK5 (0.55) | ADORA3ADORA2AADORA2BADORA1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320034-B1 | New immunologically active synthetic peptides useful for preparing an antimalarial vaccine | ENIRICERCHE SPA (IT) | 1994-08-31 | — | — | EP | disclosed |
| US-4956449-A | Forming polypeptides from tetrapeptides condensed and separated by chromatography | ENIRICERCHE, S.P.A. (IT) | 1990-09-11 | — | — | US | disclosed |
| EP-0320034-A2 | New immunologically active synthetic peptides useful for preparing an antimalarial vaccine | ENIRICERCHE S.p.A. (IT) | 1989-06-14 | — | — | EP | disclosed |