Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 13/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286680 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BIRAK4GSK3B | |
| SCHEMBL7285264 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BGPR119 | |
| SCHEMBL7285015 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BIRAK4GPR119 | |
| SCHEMBL8884076 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BGPR119 | |
| SCHEMBL7283463 | 0.79 | ITGB3 (0.49) | ITGB3ITGA2BIRAK4GPR119 | |
| Hydrochloric Acid SCHEMBL7275246 | 0.79 | ITGB3 (0.58) | ITGB3ITGA2BIRAK4GPR119 | |
| SCHEMBL7318086 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BIRAK4 | |
| SCHEMBL7323680 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BGPR119 | |
| Hydrochloric Acid SCHEMBL7275160 | 0.78 | ITGB3 (0.58) | ITGB3ITGA2BIRAK4GPR119 | |
| SCHEMBL7277677 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2BIRAK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |