Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 6/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 4/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318086 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BCTSCCYP11B1CYP11B2 | |
| SCHEMBL7285264 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BGPR119 | |
| SCHEMBL8884076 | 0.86 | ITGB3 (0.52) | ITGB3ITGA2BGPR119 | |
| SCHEMBL7798146 | 0.84 | ITGB3 (0.57) | ITGB3ITGA2BGPR119MIF | |
| SCHEMBL7285015 | 0.83 | ITGB3 (0.49) | ITGB3ITGA2BGPR119CTSCTRPA1 | |
| SCHEMBL7283463 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BGPR119EGLN2 | |
| SCHEMBL7277677 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BGPR119CTSC | |
| SCHEMBL7275877 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BGPR119EGLN2CTSC | |
| SCHEMBL7277406 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BGPR119 | |
| SCHEMBL7286097 | 0.78 | ITGB3 (0.44) | ITGB3ITGA2BGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |