Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276043 | 0.88 | EP300 (0.39) | ACHEEP300HTR2A | |
| SCHEMBL7275885 | 0.86 | EP300 (0.40) | ACHEEP300HTR2A | |
| SCHEMBL7285879 | 0.85 | BCHE (0.33) | ACHEEP300HTR2ABCHEFNTA | |
| SCHEMBL7282764 | 0.79 | ABCB1 (0.42) | HTR2A | |
| SCHEMBL7274156 | 0.79 | ABCB1 (0.42) | HTR2A | |
| SCHEMBL7283159 | 0.79 | ABCB1 (0.42) | HTR2A | |
| SCHEMBL7275535 | 0.79 | CCR3 (0.43) | HTR2A | |
| SCHEMBL7280648 | 0.78 | HTR1A (0.41) | HTR2A | |
| SCHEMBL7282205 | 0.77 | ABCB1 (0.41) | HTR2A | |
| SCHEMBL7285316 | 0.75 | ITGB3 (0.37) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-B1 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-24 | — | — | EP | disclosed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |