Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266645 | 0.88 | ALDH1A1 (0.54) | TACR2HPGDCD274KMT2AALDH1A1 | |
| SCHEMBL6428470 | 0.82 | ALDH1A1 (0.55) | TACR2POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL6428465 | 0.82 | ALDH1A1 (0.55) | TACR2POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL6754301 | 0.80 | MMP8 (0.50) | TACR2POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL6754303 | 0.80 | MMP8 (0.50) | TACR2POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL8337939 | 0.80 | POLB (0.53) | TACR2HPGDCD274POLBKMT2A | |
| SCHEMBL7287023 | 0.79 | MEN1 (0.60) | TACR2HPGDCD274POLBKMT2A | |
| SCHEMBL12310426 | 0.79 | MEN1 (0.60) | TACR2HPGDCD274POLBKMT2A | |
| SCHEMBL14295176 | 0.78 | ALDH1A1 (0.54) | TACR2HPGDCD274POLBKMT2A | |
| SCHEMBL684436 | 0.78 | POLB (0.46) | TACR2HPGDCD274POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |