SCHEMBL7277481

SCHEMBL7277481

C=CCS(=O)(=O)N1CCN([C]=O)CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2185192 0.77 CA1 (0.39) MEN1KMT2A
SCHEMBL5257406 0.77 KMT2A (0.37) MEN1KMT2A
SCHEMBL2185175 0.75 CA1 (0.42) MEN1KMT2A
SCHEMBL2186390 0.74 ALDH1A1 (0.36) MEN1KMT2A
SCHEMBL2186346 0.72 CA12 (0.48)
SCHEMBL12821513 0.72 KDM4E (0.42) MEN1KMT2A
SCHEMBL2187580 0.72 KDM4E (0.42) MEN1KMT2A
SCHEMBL83829 0.72 MEN1 (0.32) MEN1KMT2A
Hydrochloric Acid SCHEMBL27646236 0.71 KDM4E (0.41) MEN1KMT2A
Ethane SCHEMBL27663543 0.69 KMT2A (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0483667-A2 Cyclic imino derivatives, process for their preparation and drugs containing them Dr. Karl Thomae GmbH (DE) 1992-05-06 EP claimed
US-5591769-A PYRROLIDINE DERIVATIVES; ANTICOAGULANTS KARL THOMAE GMBH (DE) 1997-01-07 US disclosed
US-5541343-A ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS KARL THOMAE GMBH (DE) 1996-07-30 US disclosed
EP-0483667-A2 Cyclic imino derivatives, process for their preparation and drugs containing them Dr. Karl Thomae GmbH (DE) 1992-05-06 EP disclosed