Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277575 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL1146978 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL5288950 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL3821550 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL1631413 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL1146980 | 0.73 | ALDH1A1 (0.52) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL23462497 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL1237496 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL7379812 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 | |
| SCHEMBL5324300 | 0.71 | ALDH1A1 (0.50) | ALDH1A1MAPTPTGS1SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |