SCHEMBL1146980

SCHEMBL1146980

COC(C)(C)[C@H](N)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
SLC7A5 Q01650 2/20 0.35
GRIK1 P39086 2/20 0.31
GRM2 Q14416 1/20 0.31
GRM3 Q14832 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1146978 1.00 ALDH1A1 (0.52) ALDH1A1MAPTPTGS1SLC1A3SLC1A2
SCHEMBL18653125 0.80 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1SLC1A3SLC1A2
SCHEMBL1952232 0.75 KMT2A (0.39) ALDH1A1MAPTPTGS1
SCHEMBL1952233 0.75 KMT2A (0.39) ALDH1A1MAPTPTGS1
SCHEMBL25211968 0.74 ALDH1A1 (0.33) ALDH1A1MAPTPTGS1SLC1A3SLC1A2
SCHEMBL28819982 0.73 ALDH1A1 (0.44) ALDH1A1MAPTPTGS1SLC1A3SLC1A2
SCHEMBL7277575 0.73 ALDH1A1 (0.45) ALDH1A1MAPTPTGS1SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL14780395 0.73 DPP4 (0.34) ALDH1A1MAPTPTGS1
SCHEMBL7277580 0.73 ALDH1A1 (0.45) ALDH1A1MAPTPTGS1SLC1A3SLC1A2
SCHEMBL6433 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167507-B1 Cysteine protease inhibitors MEDIVIR AB (SE) 2016-03-02 EP claimed
US-20120220602-A1 CYSTEINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2012-08-30 US claimed
US-20110105524-A1 CYSTEINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2011-05-05 US claimed
EP-2167507-A1 CYSTEINE PROTEASE INHIBITORS Medivir AB (SE) 2010-03-31 EP claimed
US-20090023748-A1 Cysteine Protease Inhibitors MEDIVIR AB (SE) 2009-01-22 US claimed
WO-2009000877-A1 CYSTEINE PROTEASE INHIBITORS MEDIVIR AB (SE) 2008-12-31 WO claimed
WO-2008114054-A1 PROTEASE INHIBITORS MEDIVIR AB (SE) 2008-09-25 WO claimed
EP-1907503-A1 CORROSION INHIBITOR OR INTENSIFIER FOR USE IN ACIDIZING TREATMENT FLUIDS Halliburton Energy Services, Inc. (US) 2008-04-09 EP claimed
WO-2007007025-A1 CORROSION INHIBITOR OR INTENSIFIER FOR USE IN ACIDIZING TREATMENT FLUIDS HALLIBURTON ENERGY SERVICES, INC. (US) 2007-01-18 WO claimed
US-20070010404-A1 Corrosion inhibitor or intensifier for use in acidizing treatment fluids HALLIBURTON ENERGY SERVICES, INC. 2007-01-11 US claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
US-20260022102-A1 1,2,4-Oxadiazole and Thiadiazole Compounds as Immunomodulators AURIGENE ONCOLOGY LIMITED (IN) 2026-01-22 US disclosed
WO-1999011608-A1 MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS ROCHE DIAGNOSTICS GMBH (DE) 1999-03-11 WO disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105524-A1 CYSTEINE PROTEASE INHIBITORS CTSK, CTSL, CTSV ALDH1A1 3386/4885MAPT 4249/4885PTGS1 1183/4885
US-20090023748-A1 Cysteine Protease Inhibitors CTSK, CTSL, CTSV ALDH1A1 3386/4885MAPT 4249/4885PTGS1 1183/4885
US-20120220602-A1 CYSTEINE PROTEASE INHIBITORS CTSK, CTSL, CTSV ALDH1A1 3386/4885MAPT 4249/4885PTGS1 1183/4885
US-20260022102-A1 1,2,4-Oxadiazole and Thiadiazole Compounds as Immunomodulators CD274, PDCD1, PDCD1LG2 ALDH1A1 253/4885MAPT 4477/4885PTGS1 836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.