Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277581 | 1.00 | REN (0.49) | REN | |
| SCHEMBL7269524 | 0.87 | REN (0.52) | REN | |
| SCHEMBL7269528 | 0.87 | REN (0.52) | REN | |
| SCHEMBL9555781 | 0.86 | REN (0.52) | REN | |
| SCHEMBL7305280 | 0.84 | REN (0.46) | REN | |
| SCHEMBL7305274 | 0.84 | REN (0.46) | REN | |
| SCHEMBL7269967 | 0.80 | CTSC (0.38) | REN | |
| SCHEMBL7269979 | 0.80 | CTSC (0.38) | REN | |
| SCHEMBL9225973 | 0.80 | REN (0.59) | REN | |
| SCHEMBL9219121 | 0.79 | REN (0.63) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | claimed |