Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334900 | 0.91 | REN (0.58) | REN | |
| SCHEMBL7305156 | 0.90 | REN (0.65) | REN | |
| SCHEMBL7303652 | 0.85 | REN (0.57) | REN | |
| SCHEMBL7283264 | 0.84 | REN (0.57) | REN | |
| SCHEMBL7281295 | 0.83 | REN (0.69) | REN | |
| SCHEMBL9287920 | 0.83 | REN (0.69) | REN | |
| SCHEMBL9222121 | 0.82 | REN (0.55) | REN | |
| SCHEMBL8909404 | 0.81 | REN (0.62) | REN | |
| SCHEMBL9741492 | 0.80 | REN (0.52) | REN | |
| SCHEMBL9224297 | 0.80 | REN (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389616-A | Renin inhibitor, hypotensive agent | HOFFMAN-LAROCHE INC. (US) | 1995-02-14 | — | — | US | disclosed |