Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672415 | 0.77 | NR3C1 (0.39) | HTTPPARG | |
| SCHEMBL7941005 | 0.75 | NCEH1 (0.34) | HTTPPARGSMN1; SMN2 | |
| SCHEMBL3450569 | 0.75 | NCEH1 (0.34) | HTTPPARGSMN1; SMN2 | |
| SCHEMBL11593932 | 0.75 | NCEH1 (0.34) | HTTPPARGSMN1; SMN2 | |
| SCHEMBL3682167 | 0.75 | PPARG (0.39) | PCNATHRATHRBPPARGFFAR1 | |
| SCHEMBL3682170 | 0.75 | PPARG (0.39) | PCNATHRATHRBPPARGFFAR1 | |
| Hydrochloric Acid SCHEMBL11591299 | 0.74 | ALDH1A1 (0.36) | HTTPPARGSMN1; SMN2 | |
| SCHEMBL38894 | 0.73 | ESR1 (0.46) | HTT | |
| SCHEMBL21899391 | 0.70 | SLC7A5 (0.55) | CAMK2ASLC6A2 | |
| SCHEMBL38225 | 0.70 | SLC7A5 (0.55) | CAMK2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |