Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656610 | 0.86 | NOS1 (0.35) | PRMT1ADRA1ALMNAITGB3ITGA2B | |
| SCHEMBL4429695 | 0.76 | PRMT1 (0.57) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL4092950 | 0.74 | ADRA1A (0.57) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL11708030 | 0.74 | PRMT1 (0.55) | PRMT1ADRA1APLA2G2AMAPK1LMNA | |
| SCHEMBL4094844 | 0.73 | ADRA1A (0.60) | PRMT1ADRA1APLA2G2AMAPK1PLA2G4A | |
| SCHEMBL28793865 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL2161228 | 0.72 | ALDH1A1 (0.37) | MAPK1LMNAEPHX1 | |
| SCHEMBL25859824 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL607060 | 0.71 | NOS1 (0.46) | LMNA | |
| Hydrochloric Acid SCHEMBL7295055 | 0.71 | NOS1 (0.35) | LMNAPMP22CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |