Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | ADA | P00813 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277353 | 0.89 | MTNR1A (0.49) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8535073 | 0.84 | CYP1A2 (0.50) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9207261 | 0.83 | MTNR1A (0.44) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL2480671 | 0.82 | KMT2A (0.51) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL2480670 | 0.82 | CTNNB1 (0.50) | TDP1CYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL8539991 | 0.81 | CYP1A2 (0.47) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL5252569 | 0.81 | TDP1 (0.46) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL28702695 | 0.80 | SIGMAR1 (0.52) | TDP1MTNR1AMETAP2 | |
| SCHEMBL20825094 | 0.79 | MTNR1A (0.50) | TDP1MTNR1ACYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8541658 | 0.79 | NQO2 (0.55) | TDP1MTNR1ACYP1A2CYP2C19NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |