Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945915 | 0.90 | CCKBR (0.49) | CCKBRPPARAPPARGSYKKLK7 | |
| SCHEMBL7275967 | 0.88 | KLK7 (0.49) | PPARAPPARGSYKKLK7KLK5 | |
| SCHEMBL16439602 | 0.87 | BCHE (0.47) | CCKBRPPARASYKKLK7KLK5 | |
| SCHEMBL24945916 | 0.87 | PPARA (0.48) | CCKBRPPARAPPARGSYKKLK7 | |
| SCHEMBL7284493 | 0.84 | SYK (0.46) | PPARASYKKLK7KLK5CTSS | |
| SCHEMBL7278193 | 0.84 | CTSL (0.49) | SYKCTSSCTSK | |
| SCHEMBL376018 | 0.81 | PPARA (0.61) | PPARAPPARGSYKKLK7KLK5 | |
| SCHEMBL428113 | 0.81 | PPARA (0.61) | PPARAPPARGSYKKLK7KLK5 | |
| SCHEMBL2009896 | 0.81 | PPARA (0.61) | PPARAPPARGSYKKLK7KLK5 | |
| SCHEMBL24946317 | 0.81 | KLK7 (0.45) | CCKBRPPARAPPARGSYKKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529858-A1 | 2-Piperazinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |