Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279595 | 0.89 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7272213 | 0.89 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7272203 | 0.89 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL7281930 | 0.88 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL7272288 | 0.88 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL7272036 | 0.88 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7384551 | 0.71 | ALDH1A1 (0.43) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7382673 | 0.71 | ALDH1A1 (0.43) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7325360 | 0.70 | CHRM2 (0.55) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7281412 | 0.66 | SCD5 (0.45) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456519-B1 | Piperidyloxy- and quinuclidinyloxy- isoxazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-07-13 | — | — | EP | claimed |