Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 17/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CTSE | P14091 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278101 | 0.83 | CTSS (0.38) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7280431 | 0.79 | CTSS (0.41) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7326618 | 0.77 | REN (0.43) | CTSSCTSKRENAAK1 | |
| SCHEMBL10592327 | 0.77 | CTSS (0.40) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7289842 | 0.76 | CTSS (0.37) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7290446 | 0.75 | REN (0.39) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7280957 | 0.74 | CTSS (0.42) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7278174 | 0.74 | CTSS (0.38) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7358262 | 0.74 | CTSS (0.38) | CTSSCTSKRENAAK1CTSD | |
| SCHEMBL7286725 | 0.73 | REN (0.42) | CTSSCTSKRENAAK1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |