1,2-Dichlorobenzene

1,2-Dichlorobenzene

SCHEMBL727832

Clc1ccccc1Cl.N=C=O.N=C=O

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
LMNA P02545 1/20 0.62
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
ALDH1A1 P00352 5/20 0.41
CYP2A6 P11509 4/20 0.38
CYP1A2 P05177 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
PTPRC P08575 1/20 0.37
PNMT P11086 1/20 0.36
IDO1 P14902 1/20 0.36
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL2713069 1.00 TSHR (0.62) TSHRLMNACES2CES1ALDH1A1
1,2-Dichlorobenzene SCHEMBL9174409 0.97 TSHR (0.59) TSHRLMNACES2CES1ALDH1A1
SCHEMBL30159729 0.86 PTPRC (0.52) TSHRLMNAALDH1A1CYP2A6MEN1
SCHEMBL10343329 0.86 PTPRC (0.52) TSHRLMNAALDH1A1CYP2A6MEN1
SCHEMBL10316768 0.82 LMNA (0.41) TSHRLMNACES2CES1ALDH1A1
SCHEMBL2815413 0.82 TSHR (0.41) TSHRLMNACES2CES1ALDH1A1
SCHEMBL3734203 0.82 TSHR (0.41) TSHRLMNACES2CES1ALDH1A1
1,2-Dichlorobenzene SCHEMBL4958544 0.81 TSHR (0.62) TSHRLMNACES2CES1ALDH1A1
SCHEMBL6156142 0.80 TSHR (0.46) TSHRLMNACES2CES1ALDH1A1
1,2-Dichlorobenzene SCHEMBL1155123 0.79 TSHR (1.00) TSHRLMNACES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384512-B Preparation method of solvent-free anti-Stokes light-changing oil based on carbon quantum dot modified partial isocyanate group 江苏众立生包装科技有限公司 2024-03-29 CN claimed
CN-117384512-A Preparation method of solvent-free anti-Stokes light-changing oil based on carbon quantum dot modified partial isocyanate group 江苏众立生包装科技有限公司 2024-01-12 CN claimed
CN-116751553-A Double-component polyurethane sealant and application thereof in unmanned aerial vehicle field 东莞市博翔电子材料有限公司 2023-09-15 CN claimed
CN-116410436-A Preparation method and application of carboxyl-terminated hyperbranched polyamide internal crosslinking modified aqueous polyurea 扬州市祥华新材料科技有限公司 2023-07-11 CN claimed
CN-116122057-A High-strength cold-resistant textile for aerospace use and manufacturing method thereof 西京学院 2023-05-16 CN claimed
CN-116084181-A Flexible stab-resistant and bulletproof textile and manufacturing method thereof 西京学院 2023-05-09 CN claimed
US-9808554-B2 Super soft foams COVIDIEN LP (US) 2017-11-07 US claimed
US-20140330235-A1 SUPER SOFT FOAMS KPR U.S., LLC 2014-11-06 US claimed
JP-4808844-B2 2011-11-02 JP claimed
EP-1981921-A2 SUPER SOFT FOAMS Tyco Healthcare Group LP (US) 2008-10-22 EP claimed
US-6908681-B2 Silane copolymer coatings C.R. BARD, INC. (US) 2005-06-21 US claimed
EP-1310514-A2 A silane copolymer and process for preparing the same C.R. Bard Inc. (US) 2003-05-14 EP claimed
EP-1129119-B1 SILANE COPOLYMER COATINGS BARD INC C R (US) 2003-04-02 EP claimed
US-20020128419-A1 Silane copolymer coatings TERRY RICHARD N (US) 2002-09-12 US claimed
US-6329488-B1 MEDICAL DEVICES, SUCH CATHETERS HAVING COATING C. R. BARD, INC. 2001-12-11 US claimed
EP-1129119-A2 SILANE COPOLYMER COATINGS C.R. Bard Inc. (US) 2001-09-05 EP claimed
WO-2000027897-A2 SILANE COPOLYMER COATINGS C.R. BARD, INC. (US) 2000-05-18 WO claimed
EP-0106004-B1 METHOD OF FORMING A HYDROPHILIC COATING ON A SUBSTRATE Astra Tech Aktiebolag (SE) 1988-01-07 EP claimed
EP-0106004-A1 Method of forming a hydrophilic coating on a substrate Astra Tech Aktiebolag (SE) 1984-04-25 EP claimed
US-4373009-A Method of forming a hydrophilic coating on a substrate INTERNATIONAL SILICONE CORPORATION (US) 1983-02-08 US claimed