Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288646 | 0.86 | APOBEC3A (0.43) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL7279260 | 0.81 | ROCK2 (0.37) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL7291657 | 0.78 | MAPT (0.41) | HSD17B10ADH1BADH1AADH7MAPT | |
| SCHEMBL9966023 | 0.77 | L3MBTL1 (0.35) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL8882150 | 0.75 | NPC1 (0.36) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL7291628 | 0.75 | KDM4E (0.35) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL12705 | 0.74 | — | — | |
| SCHEMBL7392164 | 0.73 | L3MBTL1 (0.36) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL9963365 | 0.73 | KDM4E (0.33) | KDM4EALOX15APOBEC3AHSD17B10APOBEC3G | |
| SCHEMBL3307623 | 0.70 | ADH1B (0.31) | ADH1BADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320136-B1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-07-27 | — | — | EP | disclosed |
| EP-0311321-B1 | Heterocyclic compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-01-12 | — | — | EP | disclosed |
| EP-0283162-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-08-11 | — | — | EP | disclosed |
| EP-0274009-B1 | OXADIAZOLYLACETONITRILES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-09-09 | — | — | EP | disclosed |
| US-4999354-A | Central Nervous System Disorders, Anticonvulsant and Anxiolytic Agents | A/S FERROSAN (DK) | 1991-03-12 | — | — | US | disclosed |
| EP-0241682-B1 | NOVEL BENZODIAZEPINE DERIVATIVES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1990-11-28 | — | — | EP | disclosed |
| US-4968682-A | CENTRAL NERVOUS SYSTEM DISORDERS | A/S FERROSAN (DK) | 1990-11-06 | — | — | US | disclosed |
| US-4902686-A | Tricyclic heterocyclic compounds and their use in treating benzodiazepin receptor-related ailments | A/S FERROSAN (DK) | 1990-02-20 | — | — | US | disclosed |
| US-4886797-A | CENTRAL NERVOUS SYSTEM DISORDERS | A/S FERROSAN (DK) | 1989-12-12 | — | — | US | disclosed |
| US-4880799-A | CENTRAL NERVOUS SYSTEM DISORDERS, ANTICONVULSANTS | A/S FERROSAN (DK) | 1989-11-14 | — | — | US | disclosed |
| EP-0283162-A2 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-09-21 | — | — | EP | disclosed |
| US-4772599-A | ANTICONVULSANTS, ANXIOLYTICS, HYPNOTICS, NOOTROPICS | A/S FERROSAN (DK) | 1988-09-20 | — | — | US | disclosed |
| US-4771051-A | CENTRAL NERVOUS SYSTEM DISORDERS | A/S FERROSAN (DK) | 1988-09-13 | — | — | US | disclosed |
| US-4727153-A | NERVOUS SYSTEM DISORDERS | A/S FERROSAN (DK) | 1988-02-23 | — | — | US | disclosed |
| EP-0241682-A2 | Novel benzodiazepine derivatives and their preparation and use | NOVO NORDISK A/S (DK) | 1987-10-21 | — | — | EP | disclosed |
| EP-0226282-A2 | Heterocyclic compounds and their preparation and use | A/S FERROSAN (DK) | 1987-06-24 | — | — | EP | disclosed |
| EP-0225013-A1 | Heterocyclic compounds and their preparation and use | A/S FERROSAN (DK) | 1987-06-10 | — | — | EP | disclosed |
| US-4670433-A | CARDIOVASCULAR DISORDERS | A/S FERROSAN (DK) | 1987-06-02 | — | — | US | disclosed |
| EP-0220845-A1 | Heterocyclic compounds and their preparation and use | A/S FERROSAN (DK) | 1987-05-06 | — | — | EP | disclosed |
| EP-0197282-A1 | Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds | A/S FERROSAN (DK) | 1986-10-15 | — | — | EP | disclosed |