Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.59 |
| ▸ | MME | P08473 | 3/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278549 | 1.00 | CAPN1 (0.59) | CAPN1MMEPSMB5CTSLCTSB | |
| SCHEMBL11123914 | 0.93 | CTSL (0.54) | CAPN1MMECTSLCTSB | |
| SCHEMBL11123913 | 0.93 | CTSL (0.54) | CAPN1MMECTSLCTSB | |
| SCHEMBL7266645 | 0.90 | CAPN1 (0.62) | CAPN1MMECTSLCTSBECE1 | |
| SCHEMBL7758997 | 0.88 | ITGB3 (0.58) | MMECTSL | |
| SCHEMBL2185240 | 0.88 | ITGB3 (0.58) | MMECTSL | |
| SCHEMBL844471 | 0.88 | ITGB3 (0.58) | MMECTSL | |
| SCHEMBL21219280 | 0.87 | CAPN1 (0.74) | CAPN1MMECTSLCTSBECE1 | |
| SCHEMBL21219352 | 0.87 | CAPN1 (0.74) | CAPN1MMECTSLCTSBECE1 | |
| SCHEMBL21219351 | 0.87 | CAPN1 (0.74) | CAPN1MMECTSLCTSBECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |