Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 4/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.45 |
| ▸ | F7 | P08709 | 4/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | F3 | P13726 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271123 | 0.86 | F2 (0.48) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10600559 | 0.84 | F2 (0.47) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL9813732 | 0.84 | F2 (0.47) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10866599 | 0.84 | F2 (0.45) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10784225 | 0.84 | F2 (0.47) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10783267 | 0.83 | NPSR1 (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10778740 | 0.83 | F2 (0.44) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL7311447 | 0.83 | CTSL (0.46) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL10346671 | 0.83 | NPSR1 (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL2116716 | 0.83 | CTSL (0.46) | F2F10PRSS1F7PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833268-A | PARKINSON*S DISEASE, ANTIDEPRESSANTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0112606-A1 | Threo-adrenalinecarboxylic acid, processes for the production thereof, and pharmaceutical compositions thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-07-04 | — | — | EP | disclosed |