Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | FSHR | P23945 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271381 | 0.94 | ALDH1A1 (0.48) | AGTR1LTB4R2ABCB11GP6ALDH1A1 | |
| SCHEMBL2989 | 0.91 | FFAR1 (0.43) | AGTR1LTB4R2ABCB11GP6ALDH1A1 | |
| SCHEMBL6509546 | 0.87 | ALDH1A1 (0.49) | AGTR1LTB4R2ABCB11GP6ALDH1A1 | |
| SCHEMBL7278662 | 0.86 | MME (0.44) | AGTR1LTB4R2ABCB11GP6ALDH1A1 | |
| SCHEMBL1810055 | 0.85 | AGTR1 (0.64) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL1810051 | 0.85 | AGTR1 (0.64) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL1820 | 0.85 | FFAR1 (0.43) | AGTR1LTB4R2ABCB11GP6ALDH1A1 | |
| SCHEMBL2651 | 0.81 | ALDH1A1 (0.52) | AGTR1LTB4R2ABCB11GP6ALDH1A1 | |
| SCHEMBL2443439 | 0.81 | LTB4R2 (0.44) | AGTR1LTB4R2ABCB11GP6FFAR1 | |
| SCHEMBL3085 | 0.79 | AGTR1 (0.55) | AGTR1LTB4R2ABCB11GP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |