Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.30 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7278550 | 0.99 | PLA2G10 (0.44) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7296978 | 0.94 | PLA2G10 (0.43) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7296969 | 0.94 | PLA2G10 (0.43) | PLA2G10PLA2G5PKMGAAPOLB | |
| Oxalic Acid SCHEMBL7298168 | 0.90 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAAPOLB | |
| Oxalic Acid SCHEMBL7298195 | 0.90 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7314096 | 0.84 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAAPOLB | |
| Oxalic Acid SCHEMBL7298013 | 0.84 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAAPOLB | |
| Oxalic Acid SCHEMBL7298024 | 0.84 | PLA2G10 (0.41) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7285097 | 0.82 | PLA2G10 (0.60) | PLA2G10PLA2G5PKMGAAPOLB | |
| SCHEMBL7366324 | 0.82 | PKM (0.44) | PKMGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529858-B1 | 2-Piperazinone compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5294713-A | Inhibiting cell adhesion | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0529858-A1 | 2-Piperazinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |