Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448759 | 0.81 | EPHX1 (0.45) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL7883350 | 0.80 | SLC7A5 (0.44) | SLC15A1SMN1; SMN2ALDH1A1SLC7A5MAPT | |
| SCHEMBL7609352 | 0.80 | EPHX1 (0.48) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL8435788 | 0.80 | ALDH1A1 (0.47) | SLC15A1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL8964483 | 0.80 | ALDH1A1 (0.47) | SLC15A1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2505997 | 0.80 | ALDH1A1 (0.47) | SLC15A1RAB9ANPC1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL7394658 | 0.78 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2505994 | 0.78 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL10586047 | 0.78 | SLC15A1 (0.39) | SLC15A1RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL590532 | 0.75 | EPHX1 (0.59) | RAB9AHPGDEPHX1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |